Clinical Formulation

OUR
SCIENCE

Perfected by science.

We don't select ingredients because they trend. We select them because clinical evidence demonstrates measurable performance on real skin. Every active in the Kotiva range has a reason to be there.

Hero Active

Niacinamide
Pore Minimizing & Tone Evening

Why We Use It

THE MOST
VERSATILE
ACTIVE IN
SKINCARE

Niacinamide (Vitamin B3) is clinically proven to reduce pore appearance, even skin tone, calm inflammation, and regulate sebum — making it our most widely deployed active ingredient across the Kotiva range.

At 1%, we achieve measurable efficacy without the irritation risk that comes with higher concentrations in compromised skin barriers. Precision concentration. Proven results.

Shop Products With Niacinamide

Ingredient Library

THE ACTIVES
WE TRUST

Every ingredient in the Kotiva range is selected based on clinical evidence, safety profile, and compatibility with the specific skin types it targets.

Browse the full ingredient glossary →

Formulation Philosophy

HOW WE BUILD
A PRODUCT

Step 01
Identify the Skin Reality
We start with a real skin concern, not a market gap. Oily and acne-prone skin needs oil regulation and pore clearing — not a generic cleanser. We define the biological target first.
Step 02
Select the Active
We shortlist only ingredients with published clinical evidence for the identified concern. We review concentration data, compatibility matrices, and contraindication profiles before selection.
Step 03
Optimise the Concentration
More is rarely better in cosmeceuticals. We formulate at clinically effective concentrations — not maximum doses — to maximise efficacy while preserving skin barrier integrity.
Step 04
Doctor Review
Every formula is guided by expert insight and selected according to dermatological research, in compliance with stringent European Union manufacturing standards.
Step 05
Verify Free-From Status
Where safety data supports it, we formulate free from parabens, sulphates, and alcohol. We declare this clearly and honestly on packaging and product pages — no ambiguity.
Step 06
Set the Standard
The final product only carries the kotiva™ mark when it meets every benchmark in our formulation and validation process. The Kotiva Standard is a real standard — not a slogan.

Active Ingredients by Function

EVERY ACTIVE.
A PURPOSE.

A ribbon of amber serum folding onto pale stone, lit from behind
Hydration
Hyaluronic Acid
Sorbitol
Urea 3%
Panthenol (B5)
Vitamin B5
Brightening
Tranexamic Acid
Niacinamide
Glutathione
Pyruvic Acid
Troxerutin
Anti-Aging
Retinyl Palmitate
Coenzyme Q10
Vegetal Proteins
Ceramide Precursors
Caffeine
Clarifying
Salicylic Acid 2%
Azelaic Acid
Malic Acid
Zinc PCA
Zinc Oxide

Manufacturing Standards

MANUFACTURED
IN POLAND. EU GMP
CERTIFIED.

Every kotiva™ product is manufactured in Poland using high-quality European raw materials, in full compliance with stringent European Union manufacturing standards and Good Manufacturing Practices (GMP). Poland's advanced research institutions, skilled scientists, and state-of-the-art production facilities follow strict EU regulations to ensure quality, safety, and consistency — making it a trusted hub for the development of high-quality skincare. This same scientific rigor is why our formulations meet the standard healthcare professionals and consumers can rely on.

Ready to Apply the Science

SHOP THE
RANGE

25 doctor-approved formulations. Every ingredient selected for measurable, clinical performance.

Explore Products Find My Routine